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Scientists may have found a way to target specific receptors in the brain so that drugs may better treat the cognitive and motor problems related to schizophrenia and Alzheimer's disease.
A new study shows that nonsteroidal anti-inflammatory drugs (NSAIDs) such as the pain relievers ibuprofen and naproxen do not prevent Alzheimer's disease, but they may instead delay its onset. The study suggests a need for re-interpretation of earlier findings that suggested NSAIDs can prevent the disease. The research is published in the April 22, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology.
In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug. "Our results show that proton pump inhibitors are also antiinflammatory agents.
'It is widely believed that the processes that lead to the generation of beta amyloid plaques are a major factor in causing Alzheimer's disease. This new research looks at the activity of one of the enzymes that obstruct the plaque formation. Initial findings are showing that it is possible to kick start this enzyme into activity through its interaction with smaller compounds.
The Food and Drug Administration (FDA) has given the Blanchette Rockefeller Neurosciences Institute (BRNI) the go-ahead to conduct Phase II clinical trials of Bryostatin for the treatment of Alzheimer's disease patients. The drug showed pre-clinical efficacy to not only treat Alzheimer's disease symptoms, but also its underlying causes. "We are very excited about the FDA's agreement for BRNI to move forward with clinical trials," said Dr. Daniel Alkon, Scientific Director of BRNI.
Contrary to studies involving the not so elderly, researchers in the US found that use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as the painkillers ibuprofen and naproxen, did not delay the onset of Alzheimer's or other forms of dementia in the very elderly.
CHICAGO (Reuters) - Contrary to earlier findings, taking common painkillers such as ibuprofen and naproxen may not prevent Alzheimer's disease, but may delay it, U.S. researchers said on Wednesday. (Source: Reuters: Health)
Taking a new approach to the treatment and prevention of Alzheimer's disease, scientists have found that drug-like compounds can speed up destruction of the amyloid beta proteins that form plaque in the brains of patients with the disorder. (Source: ScienceDaily Headlines)
In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug. (Source: Huliq Health News)
A study of more than 400 Alzheimer's patients found that newer antipsychotic drugs caused weight gain and lowered good cholesterol in patients.
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