Archive for March 6th, 2010
-
Mar 06, 2010
No CommentsCognitive leisure activities and their role in preventing dementia: a systematic review
Background Dementia inflicts a tremendous burden on the healthcare system. Identifying protective factors or effective prevention strategies may lead to considerable benefits. One possible strategy mentioned in the literature relates to participation in cognitive leisure activities.Aim To determine the effectiveness of cognitive leisure activities in preventing Alzheimer's and other dementias among older adults. Types of...
-
Mar 06, 2010
No CommentsPolymorphisms in the Human Apolipoprotein E Receptor 2 Gene in Japanese Sporadic Alzheimer’s Disease Patients.
Authors: Hosoda A, Inoue T, Mao CC, Jeong YH, Yamagishi A, Ye M, Yamamoto T, Kim DH, Saeki S Apolipoprotein E (apoE) polymorphism is associated with onset of Alzheimer's disease (AD). We found seven polymorphisms in apoE receptor 2 (ApoER2), an apoE-binding receptor, in Japanese sporadic AD patients, but no association of...
-
Mar 06, 2010
No CommentsHippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer’s disease.
Authors: Takahashi H, Brasnjevic I, Rutten BP, Van Der Kolk N, Perl DP, Bouras C, Steinbusch HW, Schmitz C, Hof PR, Dickstein DL Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD). However, the underlying molecular mechanisms and the fate in the AD hippocampus of subpopulations of interneurons that...
-
Mar 06, 2010
No CommentsChanges in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau.
Authors: Dickstein DL, Brautigam H, Stockton SD, Schmeidler J, Hof PR Neurofibrillary tangles (NFTs) are composed of insoluble, hyperphosphorylated aggregates of the microtubule-associated protein tau and are present in various neurodegenerative diseases, including Alzheimer's disease (AD). To investigate how tau affects neuronal function during NFT formation and subsequent neurodegeneration, we examined the...
-
Mar 06, 2010
No CommentsDeficits in brain’s ‘executive’ skills common with TIA, minor stroke
Cognitive impairment is common in transient ischemic attack and minor ischemic stroke patients. Cognitive impairment in these patients can be detected with tests that evaluate the brain's "executive functions" -- but not with another commonly used screening designed to test for Alzheimer's dementia. (Source: ScienceDaily...
-
Mar 06, 2010
No CommentsAlzforum’s 5-Part Series On Alzheimer’s Prevention Initiative
The field is abuzz with the word "prevention," but how to pull off this vaunted goal? It's been held back by a strange Catch-22 of cost, time, and biomarker validation. That might change with a bold initiative led by Eric Reiman, Pierre Tariot, and others at the Banner Alzheimer's...
-
Mar 06, 2010
No CommentsAlzforum’s 5-Part Series On Alzheimer’s Prevention Initiative
The field is abuzz with the word "prevention," but how to pull off this vaunted goal? It's been held back by a strange Catch-22 of cost, time, and biomarker validation. That might change with a bold initiative led by Eric Reiman, Pierre Tariot, and others at the Banner Alzheimer's Institute. For the past two years,...
-
Mar 06, 2010
No CommentsNeurologists On Capitol Hill To Push For Health Care Reform
What: More than 100 neurologists from 40 states will be in Washington, DC, March 8-9, 2010, for "Neurology on the Hill," an event hosted by the American Academy of Neurology to educate lawmakers about the need for health care reform changes that consider neurologists and the patients they treat, including people with Alzheimer's disease, stroke,...
-
Mar 06, 2010
No CommentsAlzforum’s 5-Part Series On Alzheimer’s Prevention Initiative
The field is abuzz with the word "prevention," but how to pull off this vaunted goal? It's been held back by a strange Catch-22 of cost, time, and biomarker validation. That might change with a bold initiative led by Eric Reiman, Pierre Tariot, and others at the Banner Alzheimer's Institute... (Source: Alzheimer's / Dementia News...
-
Mar 06, 2010
No CommentsNeurologists On Capitol Hill To Push For Health Care Reform
What: More than 100 neurologists from 40 states will be in Washington, DC, March 8-9, 2010, for "Neurology on the Hill," an event hosted by the American Academy of Neurology to educate lawmakers about the need for health care reform changes that consider neurologists and the patients they treat, including people with Alzheimer's disease, stroke,...
