Archive for February 25th, 2010
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Feb 25, 2010
No CommentsAmiodarone-induced liver cirrhosis and parkinsonism: a case report.
Conclusions: This is the first case in which the accumulation of amiodarone in the brain was morphologically observed. Amiodarone accumulation in the brain may play a role in neurotoxicity inducing parkinsonism. PMID: 20175957 [PubMed - in process] (Source: Clinical...
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Feb 25, 2010
No CommentsHospital Stays May Spur Brain Decline in Seniors
Data collected over 13 years on 2,929 people suggests that people who were hospitalized for non-critical illnesses were 40 percent more likely to develop dementia than those who were not...
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Feb 25, 2010
No CommentsTheoretical exploration of the neural bases of behavioural disinhibition, apathy and executive dysfunction in preclinical Alzheimer’s disease in people with Down’s syndrome: potential involvement of multiple frontal-subcortical neuronal circuits
Conclusion Observed dissociation between performance on cognitive tasks associated with reported apathy and disinhibition is in keeping with proposed differences underlying neural circuitry and supports the involvement of multiple frontal-subcortical circuits in the early stages of DAT in DS. However, the prominence of disinhibition in the behavioural profile (which more closely resembles that of...
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Feb 25, 2010
No CommentsNeuroinflammation in Alzheimer’s Disease and Major Depression
Alzheimer's disease (AD) is an irreversible progressive neurodegenerative disorder and the major cause of dementia. The disease symptoms in sporadic cases usually start after the age of 60. Time between the first expression of behavioral disease symptoms and death might be up to 10 years. Thirty-five million people worldwide are estimated to suffer from AD,...
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Feb 25, 2010
No CommentsA brief summary of the articles appearing in this issue of Biological Psychiatry
Alzheimer's disease (AD) is characterized by progressive memory decline and neuropsychiatric symptoms. Profenno et al. (pages 505–512) conducted a meta-analysis of published studies on the risk for AD with obesity, diabetes and related disorders. Their results show that obesity and diabetes, which are risk factors for vascular dementia, also significantly increase risk for AD, suggesting...
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Feb 25, 2010
No CommentsThe Role of Cognitive Impairment in the Use of the Diskus Inhaler
Introduction/Objective: Background and Purpose: Drugs delivered by Metered-Dose Inhalers (MDIs) and various types of Dry Powder Inhalers (DPIs) are a mainstay in the treatment of chronic lung disease. However, previous studies suggest cognitive impairment hinders proper use of inhalers, thereby compromising their potential benefit for people with Alzheimer's disease and related dementias. Since chronic lung...
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Feb 25, 2010
No CommentsUnintentional Weight Loss in Long Term Care Residents with Alzheimer’s Disease and Weight Response with the Use of Docosahexaenoic Acid (DHA)/Eicosapentaenoic Acid (EPA) and Bioflavinoids: A Case Series
Introduction/Objective: Cachexia/dehydration may be the immediate cause of death in the end stage of dementia in as many as 35% of nursing home residents. Cachexia is associated with suppressed appetite, food intake and body weight while proinflammatory cytokines are increased. Proinflammatory cytokines directly result in feeding suppression and lower intake of nutrients and cachexia is...
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Feb 25, 2010
No CommentsVisual Stimulation: An Approach to Weight Loss in Long Term Care
Introduction/Objective: Excessive weight loss in long term care is common and is frequently targeted as a quality measure. It has been demonstrated previously that food consumption in patients with advanced Alzheimer's disease can be increased through use of brightly colored dinnerware to overcome diminished sensitivity to visual contrast. Our pilot program seeks to generalize the...
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Feb 25, 2010
No CommentsChart Review at the Department of Elder Affairs in Central Florida of Disease Prevalence Among Recipients of Elderly Services
To the Editor: The Department of Elder Affairs is responsible for administering human service programs for the elderly population in an effort to try to help them keep their self-sufficiency and self-determination in all possible ways. These services include case management, home-delivered meals, adult day care, caregiver support and training, medical equipment and supplies,...
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Feb 25, 2010
No CommentsNational Alzheimer’s Call Center
Funding Opportunity Number: HHS-2010-AOA-AC-1010 Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementCategory of Funding Activity: Income Security and Social ServicesCFDA Number: 93.048Eligible Applicants Others (see text field entitled "Additional Information on Eligibility" for clarification)Agency Name HHS-AoA (Source:...
