Alzheimer’s Group Resources

The Pre-Capillary Segment of the Blood-Brain Barrier and its Relation to Perivascular Drainage in Alzheimer’s Disease and Small Vessel Disease.

Fluid and protein exchange between brain and blood is regulated by the blood-brain barrier. Physiologically, this exchange is limited to the capillary segment. Under pathological conditions, leakage of plasma into the brain can be caused by degenerative disorders of cerebral arteries. It interferes with the drainage of extracellular fluid and proteins from the brain and can lead to an accumulation of proteins in the brain, especially of a protein that is related to Alzheimer's disease. (Source: TheScientificWorldJOURNAL: Newly published articles.)

Marital status and dementia risk

This study assessed the relationship between marital status in 2,000 middle-aged people (average age 50) and their cognitive impairment about 21 years later. It found that the risk of any cognitive impairment almost doubled if a person was alone in middle age compared to having a partner. Being without a partner in both middle age and later life further increased risk. Cognitive function was not measured at the start of the study, so it is difficult to prove that marital status is related to cognitive impairment in later life. If the association does exist, the reasons behind it are difficult to establish. The risk of dementia is likely to be governed by a complex interaction of several factors, such as lifetime personal, social and intellectual interactions, health, lifestyle and medical ...

Current Status Of The Development Programs Of New Indications And Formulations For Aricept(R) For Enhancing Patient Value

Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") and Eisai Corporation of North America (Headquarters: Woodcliff Lake, NJ, Chairman and CEO Hajime Shimizu) are currently focusing on three clinical development programs for the company's major product Aricept(R) (donepezil hydrochloride tablets) to further contribute to patients with Alzheimer's disease. As progress in those programs has been made, Eisai announces the status as follows: 1.

Alzheimer’s Gene Risk Higher For Those Widowed in Mid Life and Stay Without a Partner

Researchers in Sweden found that people who have the APOE Alzheimer's gene and who live alone in middle age after being widowed or separated from a life partner, are at higher risk of developing dementia. The study is the work of Dr Krister Hakannson, a research fellow at the Karolinska Institute in Stockholm, and colleagues, and is published in the 2 July online issue of the BMJ.

Does being single in midlife increase risk of dementia?

Middle-aged people living alone have twice the risk of developing dementia and Alzheimer's disease in later life compared with married or cohabiting people, according to a study published on bmj.com. (Source: Alzheimers Society)

Alzheimer’s Gene Risk Higher For Those Widowed in Mid Life and Stay Without a Partner

Researchers in Sweden found that people who have the APOE Alzheimer's gene and who live alone in middle age after being widowed or separated from a life partner, are at higher risk of developing dementia. The study is the work of Dr Krister Hakannson, a research fellow at the Karolinska Institute in Stockholm, and colleagues, and is published in the 2 July online issue of the BMJ. (Source: Health News from Medical News Today)

Current Status Of The Development Programs Of New Indications And Formulations For Aricept(R) For Enhancing Patient Value

Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") and Eisai Corporation of North America (Headquarters: Woodcliff Lake, NJ, Chairman and CEO Hajime Shimizu) are currently focusing on three clinical development programs for the company's major product Aricept(R) (donepezil hydrochloride tablets) to further contribute to patients with Alzheimer's disease. (Source: Health News from Medical News Today)