Archive for February 17th, 2009
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Feb 17, 2009
No CommentsCSF APPs{alpha} and Phosphorylated Tau Protein Levels in Mild Cognitive Impairment and Dementia of Alzheimer’s Type
We exploratively measured APPs, a secreted fragment of the non-amyloidogenic cleavage of amyloid precursor protein via a-secretase, and tau protein phosphorylated at threonine 181 (ptau) in the cerebrospinal fluid of 10 patients with mild cognitive impairment, 20 patients with dementia of Alzheimer's type, and 10 controls. Cerebrospinal fluid APPs and ptau levels were correlated with...
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Feb 17, 2009
No CommentsAssociation of ACE I/D Gene Polymorphism With Vascular Dementia: A Meta-Analysis
Conclusions: The angiotensin-converting enzyme insertion/deletion polymorphism might be neutral to vascular dementia. (Source: Journal of Geriatric Psychiatry and...
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Feb 17, 2009
No CommentsAlterations in Regional Brain Volume and Individual MRI-Guided Perfusion in Normal Control, Stable Mild Cognitive Impairment, and MCI-AD Converter
Regional differences in tissue volume and perfusion in brains of individuals with mild cognitive impairment (MCI) versus normal healthy age-matched controls (NC), and the differences between MCI-AD converters and stable MCI patients were investigated. MRI and SPECT scans were performed on 13 MCI (74+6 years) and 12 NC (75+4 years). Of the MCI patients, 10...
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Feb 17, 2009
No CommentsPrimary care and dementia: 1. diagnosis, screening and disclosure
To write a narrative review of the roles of primary care practitioners in caring for people with dementia in the community.The systematic review carried out for the NICE/SCIE Guidelines was updated from January 2006, Cochrane Reviews were identified, and other publications found by consultation with experts.The insidious and very variable development of dementia syndromes makes...
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Feb 17, 2009
No CommentsNew kind of epilepsy shakes up memory
A newly revealed condition is challenging our assumption of how memories are formed - it may lead to more effective treatments for disorders like Alzheimer's and dementia (Source: New Scientist - The Human Brain)MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news...
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Feb 17, 2009
1 CommentMediterranean Diet May Protect Against Mild Cognitive Impairment
Elderly individuals who follow a healthy Mediterranean diet are less likely to develop mild cognitive impairment and to convert from mild cognitive impairment to Alzheimer's disease. Medscape Medical News (Source: Medscape Medical News...
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Feb 17, 2009
No CommentsTerry Pratchett: We need to talk about dementia
Cassandra Jardine examines how Terry Pratchett and other public figures have brought a Cinderella illness into the spotlight. (Source: Telegraph...
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Feb 17, 2009
No CommentsActeylcholinesterase inhibitor rivastigmine enhances cellular defenses in neuronal and macrophage-like cell lines.
Authors: Zhou X, Patel AR, Perez F, Jurivich DA Neuroprotection mediated by the cellular heat shock response offers 1 clinical strategy to prevent, stabilize, and possibly reverse neurodegenerative processes. Although damaged proteins are thought to be the primary stimulus for the heat shock response, several studies indicate that pharmaceutical agents can either...
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Feb 17, 2009
No CommentsLlamas May Be Key to New Treatments
Scientists are exploiting an unusual feature of llamas' immune system to develop treatments for rheumatoid arthritis, cancer and Alzheimer's. (Source: WSJ.com:...
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Feb 17, 2009
No CommentsInjection boosts memory in Alzheimer’s animals
Injections of a nerve-growth protein improved memory and learning in both rodents and primates with animal versions of the disease (Source: New Scientist - Health)MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news...
